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MICROBIOLOGY (MICRO44080)

Submit  Message: MICROBIOLOGY (MICRO44080) Assessment 2020 General instructions Chemical biology is a multidisciplinary science. The area of natural product-based drug discovery requires collaboration between chemists and biologists, namely microbiologists, biochemists, pharmacologists. Microbiologists contribute by isolating micro-organisms that synthesise new antibiotics and other bioactive compounds, by sequencing biosynthetic gene clusters, by genetic engineering of producer strains to make new analogues in high yields, and by extracting and purifying new compounds from fermentation cultures. Read the three research papers listed. Briefly outline the background to and motivation for the research presented. Then explain the content of each paper in your own words, concentrating on areas of interest to microbiologist and finally state what these three studies have achieved. 

The guideline word count is 1000 with an upper limit of 1500. Marks are awarded for: 

1) knowledge and understanding of the topic, 

2) ability to identify and summarise the most important information, 

3) effective communication of key points, 

4) ability to explain the significance of the work. You are expected to focus on aspects that were covered in the lecture course. 

Detail on chemical structure determination by NMR or X-ray crystallography, or organic synthesis only need to be briefly mentioned.

Submit  Message: MICROBIOLOGY (MICRO44080) Assessment 2020 General instructions Chemical biology is a multidisciplinary science. The area of natural product-based drug discovery requires collaboration between chemists and biologists, namely microbiologists, biochemists, pharmacologists. Microbiologists contribute by isolating micro-organisms that synthesise new antibiotics and other bioactive compounds, by sequencing biosynthetic gene clusters, by genetic engineering of producer strains to make new analogues in high yields, and by extracting and purifying new compounds from fermentation cultures. Read the three research papers listed. Briefly outline the background to and motivation for the research presented. Then explain the content of each paper in your own words, concentrating on areas of interest to microbiologist and finally state what these three studies have achieved. 

The guideline word count is 1000 with an upper limit of 1500. Marks are awarded for: 

1) knowledge and understanding of the topic, 

2) ability to identify and summarise the most important information, 

3) effective communication of key points, 

4) ability to explain the significance of the work. You are expected to focus on aspects that were covered in the lecture course. 

Detail on chemical structure determination by NMR or X-ray crystallography, or organic synthesis only need to be briefly mentioned.

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