QuestionQuestion 12 / 2 ptsIn hemolytic anemia, jaundice occurs o

QuestionQuestion 12 / 2 ptsIn hemolytic anemia, jaundice occurs only whenthe patient has elevations in aspartate transaminase (AST) and alanine transaminase (ALT).heme destruction exceeds the liver’s ability to conjugate and excrete bilirubin.the erythrocytes are coated with an immunoglobulin.erythrocytes are destroyed in the spleen.Question 22 / 2 ptsSymptoms of polycythemia vera are mainly the result ofdestruction of erythrocytes.neurologic involvement.increased blood viscosity.a decreased erythrocyte count.Question 32 / 2 ptsThe underlying disorder of _____ anemia is defective secretion of intrinsic factor, which is essential for the absorption of vitamin B12.perniciousmicrocytichypochromichemolyticQuestion 42 / 2 ptsPernicious anemia generally requires continued therapy lasting8 to 12 months.the rest of one’s life.until the iron level is normal.6 to 8 weeks.Question 52 / 2 ptsIn some anemias, the erythrocytes are present in various sizes, which is referred to asmicrocytosis.poikilocytosis.isocytosis.anisocytosis.Question 62 / 2 ptsUntreated pernicious anemia is fatal, usually because ofrenal failure.heart failure.brain hypoxia.liver hypoxia.Question 70 / 2 ptsLocal signs and symptoms of Hodgkin disease–related lymphadenopathy are a result ofinflammation and ischemia.obstruction and pressure.ischemia and pressure.pressure and obstruction.Question 82 / 2 ptsWhat is the most common cause of vitamin K deficiency?An IgG-mediated autoimmune disorderLiver failureTotal parenteral nutrition (TPN) with antibiotic therapyAdministration of warfarin (Coumadin)Question 92 / 2 ptsHeparin-induced thrombocytopenia (HIT) is described as a(n)IgG immune-mediated adverse drug reaction that reduces circulating platelets.hematologic reaction to heparin in which the bone marrow is unable to produce sufficient platelets to meet the body’s needs.cell-mediated drug reaction in which macrophages process the heparin and platelet complexes that are then destroyed by activated cytotoxic T cells.IgE-mediated allergic drug reaction that reduces circulating platelets.Question 102 / 2 ptsWhich proinflammatory cytokines are responsible for the development and maintenance of DIC?Tumor necrosis factor-alpha (TNF-a); IL-1, IL-6, and IL-8; and platelet-activatingfactor (PAF)Granulocyte-macrophage colony-stimulating factor (GM-CSF); IL-3, IL-5, and IL-9, and IFN-?Granulocyte colony-stimulating factor (G-CSF); IL-2, IL-4, and IL-10; and IFN-?Macrophage colony-stimulating factor (M-CSF); IL-7, IL-11, and IL-14; and PAFQuestion 112 / 2 ptsG6PD and sickle cell disease arediagnosed equally in men and women.inherited autosomal recessive disorders.inherited X-linked recessive disorders.disorders initiated by hypoxemia and acidosis.Question 122 / 2 ptsThe sickle cell trait differs from sickle cell disease in that the child with sickle cell traithas the mildest form of the disease with normal hemoglobin and hemoglobin F, which prevents sickling.has a mild form of sickle cell disease that causes sickling during fever and infection, but not during acidosis or hypoxia, whereas the child with sickle cells disease develops sickling during each of these conditions.has a milder form of the disease that is characterized by vaso-occlusive crises and is believed to result from higher hemoglobin values and viscosity.inherited normal hemoglobin A from one parent and Hb S from the other parent, whereas the child with sickle cell disease has Hb S from both parents.Question 132 / 2 ptsHemolytic disease of the newborn can occur if the mother istype AB blood and the fetus has type B.Rh-positive and the fetus is Rh-negative.Rh-negative and the fetus is Rh-positive.type A blood and the fetus has type O.Question 142 / 2 ptsWhat is the name of the disorder in which levels of bilirubin remain excessively high in the newborn and are deposited in the brain?Icterus gravis neonatorumJaundiceKernicterusIcterus neonatorumQuestion 152 / 2 ptsIn a full-term infant, the normal erythrocyte life span is _____ days, whereas the adult is _____ days.30 to 50; 8060 to 80; 120120 to 130; 15090 to 110; 140Question 160 / 2 ptsIdiopathic thrombocytopenic purpura (ITP) is an autoimmune process involving antibodies againsteosinophils.basophils.neutrophils.platelets.Question 172 / 2 ptsCardiac cells can withstand ischemic conditions and still return to a viable state for how many minutes?15102520Question 180 / 2 ptsThe risk of developing coronary artery disease is increased up to threefold byobesity.hypertension.high alcohol consumption.diabetes mellitus.Question 190 / 2 ptsWhat alteration occurs in injured endothelial cells that contributes to atherosclerosis?They are unable to make the normal amount of vasodilating cytokines.They produce an increased amount of antithrombotic cytokines.They develop a hypersensitivity to homocysteine and lipids.They release toxic oxygen radicals that oxidize low-density lipoproteins (LDLs).Question 202 / 2 ptsIn systolic heart failure, what effect does angiotensin II have on stroke volume?Increases preload and decreases afterloadIncreases preload and increases afterloadDecreases preload and decreases afterloadDecreases preload and increases afterloadQuestion 212 / 2 ptsWhat is the most important clinical manifestation of aortic coarctation in the neonate?Congestive heart failure (CHF)Cor pulmonaleCerebral hypertensionPulmonary hypertensionQuestion 222 / 2 ptsWhen does most cardiovascular development occur?Between the 12th and 14th weeks of gestationBetween the eighth and 10th weeks of gestationBy the 28th day of gestationBetween the fourth and seventh weeks of gestationQuestion 232 / 2 ptsWhich heart defect produces a systolic ejection murmur at the right upper sternal border that transmits to the neck and left lower sternal border with an occasional ejection click?Pulmonic stenosisHypoplastic left heart syndromeAortic stenosisCoarctation of the aortaQuestion 242 / 2 ptsWhich congenital heart defects occur in trisomy 13, trisomy 18, and Down syndrome?Coarctation of the aorta and pulmonary stenosisTetralogy of Fallot and persistent truncus arteriosusAtrial septal defect and dextrocardiaVentricular septal defect and patent ductus arteriosusQuestion 252 / 2 ptsThe foramen ovale is covered by a flap that creates a check valve allowing blood to flow unidirectionally from the _____ to the _____.right atrium; left atriumright atrium; right ventricleright ventricle; left ventricleleft atrium; left ventricle

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